Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 13/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647750 | 1.00 | PYGL (0.39) | PYGLMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1293594 | 1.00 | PYGL (0.39) | PYGLMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL12107494 | 1.00 | PYGL (0.39) | PYGLMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1293592 | 1.00 | PYGL (0.39) | PYGLMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL15127692 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL15106702 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL754149 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL17563566 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL13635811 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL12159997 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499115-B1 | PROCESS FOR PREPARING HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB HOLDINGS IRELAND (CH) | 2016-07-27 | — | — | EP | disclosed |