Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 8/20 | 0.46 |
| ▸ | NPY4R | P50391 | 8/20 | 0.42 |
| ▸ | NPY1R | P25929 | 6/20 | 0.42 |
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422680 | 0.89 | KISS1R (0.47) | KISS1RNPY4R | |
| SCHEMBL30092982 | 0.86 | NPY4R (0.48) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31307247 | 0.85 | KISS1R (0.49) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17948378 | 0.85 | KISS1R (0.49) | KISS1R | |
| SCHEMBL31307257 | 0.84 | KISS1R (0.50) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30140921 | 0.84 | TFPI (0.48) | — | |
| SCHEMBL16509013 | 0.83 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30350530 | 0.82 | NPY4R (0.47) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31307230 | 0.82 | KISS1R (0.48) | KISS1RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30924751 | 0.81 | TFPI (0.44) | KISS1RNPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215033-A1 | Granulocyte Macrophage Colony-Stimulating Factor Compositions | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215033-A1 | Granulocyte Macrophage Colony-Stimulating Factor Compositions | CSF3R, CSF1R, GMFG | KISS1R 3793/4885NPY4R 3582/4885NPY1R 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.