SCHEMBL1795138

SCHEMBL1795138

CCCCCCCC1(CCCCCCC)c2cc(Br)ccc2-c2ccc(Br)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
MMP2 P08253 4/20 0.36
MMP9 P14780 4/20 0.36
MMP8 P22894 4/20 0.36
MMP13 P45452 4/20 0.36
CYP1A2 P05177 3/20 0.36
CYP2D6 P10635 3/20 0.36
CYP2C19 P33261 3/20 0.36
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PDK2 Q15119 2/20 0.35
CNR1 P21554 4/20 0.34
CNR2 P34972 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466119 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL197316 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL30945125 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL31065067 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL4532916 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL197894 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL13708994 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL13555215 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL196456 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13
SCHEMBL29230367 1.00 LMNA (0.36) LMNAMMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9198985-B2 Bimodal star polymer architectures as fluorescent and MRI imaging reagents VANDERBUILT UNIVERSITY (US) 2015-12-01 US disclosed
US-20130029369-A1 BIMODAL STAR POLYMER ARCHITECTURES AS FLUORESCENT AND MRI IMAGING REAGENTS NATIONAL SCIENCE FOUNDATION 2013-01-31 US disclosed
US-20110284830-A1 POLYMER AND POLYMER-NANOPARTICLE COMPOSITIONS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2011-11-24 US disclosed
US-7951874-B2 Non-conjugated polymeric perarylated boranes, use thereof as organically semiconductor transmitters and/or transport materials, methods for producing same and uses thereof OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2011-05-31 US disclosed
US-7858724-B2 Polymeric, phosphorescent, organically semi-conductive emitter materials based on perarylated boranes, method for their production and use thereof OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2010-12-28 US disclosed
US-7750112-B2 Polymers comprising benzotriazole for use in optical devices CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-06 US disclosed
EP-1620492-B9 NON-CONJUGATED POLYMERIC PERARYLATED BORANES, USE THEREOF AS ORGANICALLY SEMICONDUCTING TRANSMITTERS AND/OR TRANSPORT MATERIALS, METHODS FOR PRODUCING SAME AND USES THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2009-11-04 EP disclosed
EP-1620492-B1 NON-CONJUGATED POLYMERIC PERARYLATED BORANES, USE THEREOF AS ORGANICALLY SEMICONDUCTING TRANSMITTERS AND/OR TRANSPORT MATERIALS, METHODS FOR PRODUCING SAME AND USES THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2009-03-25 EP disclosed
EP-1699898-B1 POLYMERIC, PHOSPHORESCENT, ORGANICALLY SEMI-CONDUCTIVE EMITTER MATERIALS BASED ON PERARYLATED BORANES, METHOD FOR THEIR PRODUCTION AND USE THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2008-10-29 EP disclosed
US-20070191587-A1 Polymeric, phosphorescent, organically semi-conductive emitter materials based on perarylated boranes, method for their production and use thereof OSRAM OLED GMBH (DE) 2007-08-16 US disclosed
US-20070043204-A1 Novel polymers comprising benzotriazole for use in optical devices CIBA SPECIALITY CHEMICALS CORP. 2007-02-22 US disclosed
US-20060229431-A1 Non-conjugated polymeric perarylated boranes, use thereof as organically semiconductor transmitters and/or transport materials, methods for producing same and uses thereof OSRAM OLED GMBH (DE) 2006-10-12 US disclosed
EP-1620492-A1 NON-CONJUGATED POLYMERIC PERARYLATED BORANES, USE THEREOF AS ORGANICALLY SEMICONDUCTOR TRANSMITTERS AND/OR TRANSPORT MATERIALS, METHODS FOR PRODUCING SAME AND USES THEREOF Osram Opto Semiconductors GmbH (DE) 2006-02-01 EP disclosed
WO-2004099291-A1 NON-CONJUGATED POLYMERIC PERARYLATED BORANES, USE THEREOF AS ORGANICALLY SEMICONDUCTOR TRANSMITTERS AND/OR TRANSPORT MATERIALS, METHODS FOR PRODUCING SAME AND USES THEREOF OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2004-11-18 WO disclosed