Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952856 | 0.94 | PIK3CA (0.46) | PIK3CARPS6KA3DYRK1AIMPDH2ALK | |
| SCHEMBL21046108 | 0.91 | PIK3CA (0.41) | PIK3CARPS6KA3DYRK1AIMPDH2ALK | |
| SCHEMBL22126344 | 0.88 | CYP11B2 (0.44) | PIK3CARPS6KA3CYP17A1 | |
| SCHEMBL10100905 | 0.87 | MAPK10 (0.41) | PIK3CATNFMKNK1MEN1KMT2A | |
| SCHEMBL17952770 | 0.86 | KDM4E (0.42) | RPS6KA3DYRK1ACYP1A2 | |
| SCHEMBL17952776 | 0.86 | KDM4E (0.42) | RPS6KA3DYRK1ACYP1A2 | |
| SCHEMBL15945736 | 0.86 | CDK4 (0.42) | PIK3CADYRK1AMKNK1MEN1KMT2A | |
| SCHEMBL11965527 | 0.86 | CDK4 (0.42) | PIK3CADYRK1AMKNK1MEN1KMT2A | |
| SCHEMBL28797206 | 0.85 | ATM (0.44) | PIK3CAMEN1KMT2AMAPTNR3C1 | |
| SCHEMBL15945688 | 0.84 | CDK4 (0.43) | PIK3CADYRK1ACYP1A2MKNK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |