Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19238786 | 0.89 | KDM4E (0.50) | PIK3CAKDM4EATML3MBTL1KMT2A | |
| SCHEMBL15034455 | 0.89 | KDM4E (0.46) | ASIC3SMOPIK3CAPIM1TGFBR1 | |
| SCHEMBL9889031 | 0.89 | PIK3CA (0.46) | PIK3CAKDM4EATML3MBTL1MAP4K4 | |
| SCHEMBL17952728 | 0.87 | KDM4E (0.43) | ASIC3SMOTGFBR1KDM4EATM | |
| SCHEMBL17952894 | 0.87 | KDM4E (0.43) | ASIC3SMOTGFBR1KDM4EATM | |
| SCHEMBL16855925 | 0.87 | KDM4E (0.45) | ASIC3SMOPIK3CAPIM1TGFBR1 | |
| SCHEMBL17952918 | 0.86 | KDM4E (0.48) | ASIC3SMOPIM1TGFBR1KDM4E | |
| SCHEMBL12455148 | 0.86 | PLA2G2A (0.37) | ASIC3SMOPIK3CAPIM1TGFBR1 | |
| SCHEMBL17714898 | 0.85 | KDM4E (0.41) | SMOPIK3CAKDM4EATML3MBTL1 | |
| SCHEMBL21562723 | 0.85 | SMO (0.35) | ASIC3SMOPIK3CAPIM1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |