Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610726 | 0.85 | CYP11B1 (0.54) | HSD17B1HSD17B2CYP11B1HPGDSLDHA | |
| SCHEMBL18540375 | 0.83 | CYP11B1 (0.36) | HSD17B1HSD17B2CYP11B1HPGDSLDHA | |
| SCHEMBL15421297 | 0.82 | CYP11B1 (0.50) | HSD17B1HSD17B2CYP11B1HPGDSLDHA | |
| SCHEMBL17465478 | 0.81 | CYP11B1 (0.45) | HSD17B1HSD17B2CYP11B1HPGDSLDHA | |
| SCHEMBL13910991 | 0.81 | HSD17B1 (0.63) | HSD17B1HSD17B2CYP11B1HPGDSLDHA | |
| SCHEMBL30109153 | 0.81 | CYP2A6 (0.46) | — | |
| SCHEMBL5115970 | 0.81 | CYP2A6 (0.46) | — | |
| SCHEMBL16484524 | 0.81 | CYP2A6 (0.46) | — | |
| SCHEMBL16484604 | 0.80 | NPC1 (0.47) | HSD17B1HSD17B2IDO1TDO2 | |
| SCHEMBL12957239 | 0.80 | HSD17B1 (0.67) | HSD17B1HSD17B2CYP11B1HPGDSLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |