Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938133 | 0.98 | FFAR1 (0.43) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL25573555 | 0.95 | FFAR1 (0.41) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL17938134 | 0.93 | THRA (0.41) | FFAR1RARBPTPN11PTPROTHRA | |
| SCHEMBL17938150 | 0.92 | PLK1 (0.39) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL8667344 | 0.92 | FFAR1 (0.42) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL17938129 | 0.91 | FFAR1 (0.40) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL10325691 | 0.89 | PLAU (0.40) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL17954456 | 0.89 | FFAR1 (0.40) | FFAR1RARBPLK1PTPN11PTPRO | |
| SCHEMBL17938131 | 0.88 | THRA (0.41) | FFAR1RARBPTPN11PTPROTHRA | |
| SCHEMBL21522699 | 0.88 | FFAR1 (0.41) | FFAR1RARBPTPN11PTPROTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643425-B1 | COMPOUNDS FOR A LIQUID CRYSTAL MEDIUM, AND THE USE THEREOF FOR HIGH-FREQUENCY COMPONENTS | MERCK PATENT GMBH (DE) | 2016-07-27 | — | — | EP | disclosed |