Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954518 | 0.84 | KDM4E (0.39) | SMN1; SMN2HIF1AKDM4EMEN1MAPT | |
| SCHEMBL17954493 | 0.83 | PDE6D (0.37) | PDE6DSMN1; SMN2HIF1AKDM4EMAOA | |
| SCHEMBL17954494 | 0.82 | PDE6D (0.39) | PDE6DSMN1; SMN2HIF1AKDM4EMAOA | |
| SCHEMBL18770801 | 0.77 | POLB (0.41) | PDE6DMAPTNPC1TSHRHSD17B10 | |
| SCHEMBL16629689 | 0.76 | PDE6D (0.37) | PDE6DSMN1; SMN2HIF1AKDM4EMAPT | |
| SCHEMBL17954500 | 0.74 | SMN1; SMN2 (0.40) | PDE6DSMN1; SMN2HIF1AKDM4EMAPT | |
| SCHEMBL28367605 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2HIF1AKDM4EMEN1MAPT | |
| SCHEMBL24513713 | 0.73 | ADORA1 (0.36) | SMN1; SMN2HIF1AKDM4EMEN1MAPT | |
| SCHEMBL17954492 | 0.72 | PDE6D (0.41) | PDE6DSMN1; SMN2HIF1AKDM4EMEN1 | |
| SCHEMBL22958700 | 0.72 | MAPT (0.38) | SMN1; SMN2MAPTNPSR1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247768-B1 | NAPHTHYL SUBSTITUTED ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| WO-2016116510-A1 | NAPTHYL-SUBSTITUTED ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |