Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22958702 | 0.98 | MAPT (0.37) | MAPTSMN1; SMN2NPSR1P2RX4FAAH | |
| SCHEMBL20199998 | 0.97 | MAPT (0.36) | MAPTSMN1; SMN2NPSR1P2RX4FAAH | |
| SCHEMBL22958649 | 0.97 | ALDH1A1 (0.36) | MAPTSMN1; SMN2NPSR1FAAHALDH1A1 | |
| SCHEMBL20199996 | 0.97 | MAPT (0.40) | MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1 | |
| SCHEMBL20199992 | 0.97 | MAPT (0.40) | MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1 | |
| SCHEMBL19038404 | 0.97 | ALDH1A1 (0.36) | MAPTSMN1; SMN2NPSR1FAAHALDH1A1 | |
| SCHEMBL20199989 | 0.95 | MAPT (0.35) | MAPTSMN1; SMN2NPSR1P2RX4FAAH | |
| SCHEMBL22958738 | 0.95 | MAPT (0.37) | MAPTSMN1; SMN2NPSR1P2RX4CA12 | |
| SCHEMBL15489932 | 0.95 | MAPT (0.41) | MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1 | |
| SCHEMBL31346510 | 0.95 | MAPT (0.41) | MAPTSMN1; SMN2NPSR1P2RX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210043852-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-11 | — | — | US | disclosed |