Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.68 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.68 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 5/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19618884 | 1.00 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL3113146 | 1.00 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL7897252 | 0.86 | CHRNB4 (0.63) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL10326918 | 0.81 | CHRNB4 (0.73) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL2199760 | 0.81 | CHRNB4 (1.00) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL10326531 | 0.81 | CHRNB4 (0.73) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL10326970 | 0.81 | CHRNB4 (0.73) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL2199756 | 0.81 | CHRNB4 (1.00) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H | |
| SCHEMBL17955713 | 0.80 | CNR2 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4DPP4 | |
| SCHEMBL2202866 | 0.78 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB2CHRNA4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822115-B2 | Nitrogen containing compounds and their use as antibacterial agents | WOCKHARDT LIMITED (IN) | 2017-11-21 | — | — | US | disclosed |
| US-9403835-B2 | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators | ARES TRADING S.A. (CH) | 2016-08-02 | — | — | US | disclosed |
| US-9403835-B2 | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators | ARES TRADING S.A. (CH) | 2016-08-02 | — | — | US | disclosed |