Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14684602 | 0.88 | POLB (0.44) | POLBHPGDGLAHSD17B10ALDH1A1 | |
| SCHEMBL14678088 | 0.82 | POLB (0.40) | POLBAGPAT2JAK2JAK1TYK2 | |
| SCHEMBL15868312 | 0.81 | POLB (0.37) | POLBAGPAT2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL14678186 | 0.80 | POLB (0.36) | POLBAGPAT2JAK2JAK1TYK2 | |
| SCHEMBL15868317 | 0.80 | POLB (0.38) | POLBAGPAT2JAK2JAK1TYK2 | |
| SCHEMBL14677213 | 0.79 | POLB (0.38) | POLBAGPAT2JAK2JAK1TYK2 | |
| SCHEMBL29431596 | 0.78 | POLB (0.35) | POLBAGPAT2JAK2JAK1TYK2 | |
| SCHEMBL14677038 | 0.78 | POLB (0.35) | POLBAGPAT2JAK2JAK1TYK2 | |
| SCHEMBL17009004 | 0.77 | POLB (0.37) | POLBAGPAT2KDM4EALDH1A1NPC1 | |
| SCHEMBL17896030 | 0.77 | POLB (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403771-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-02 | — | — | US | disclosed |
| US-9403771-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-02 | — | — | US | disclosed |