SCHEMBL17896030

SCHEMBL17896030

CCSc1cc(C(F)(F)F)cnc1-c1nc2cc(O)ncc2n1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.39
▸ AGBL2 Q5U5Z8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755915 0.88 POLB (0.37) POLBAGBL2
SCHEMBL17896023 0.87 POLB (0.37) POLBAGBL2
SCHEMBL17009004 0.87 POLB (0.37) POLB
SCHEMBL17901811 0.85 POLB (0.36) POLB
SCHEMBL20847335 0.85 POLB (0.36) POLB
SCHEMBL20847439 0.85 POLB (0.40) POLB
SCHEMBL14678088 0.85 POLB (0.40) POLB
SCHEMBL17901809 0.85 POLB (0.39) POLB
SCHEMBL15868312 0.84 POLB (0.37) POLB
SCHEMBL20628368 0.84 POLB (0.35) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385048-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATION AG (CH) 2019-08-20 — — US disclosed
US-10385048-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATION AG (CH) 2019-08-20 — — US disclosed
EP-3240786-B1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2019-03-27 — — EP disclosed
EP-3240786-B1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2019-03-27 — — EP disclosed
US-20170367332-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-12-28 — — US disclosed
US-20170367332-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-12-28 — — US disclosed
EP-3240786-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS Syngenta Crop Protection AG (CH) 2017-11-08 — — EP disclosed
WO-2016107831-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2016-07-07 — — WO disclosed
WO-2016107831-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2016-07-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170367332-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, SQOR, ACHE POLB 2724/4885AGBL2 2684/4885
US-10385048-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents DDT, SQOR, ACHE POLB 2724/4885AGBL2 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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