⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780480 | 0.81 | — | — | |
| SCHEMBL23202631 | 0.81 | — | — | |
| SCHEMBL15606714 | 0.79 | — | — | |
| SCHEMBL12597840 | 0.79 | FAAH (0.41) | — | |
| SCHEMBL29183039 | 0.79 | FAAH (0.41) | — | |
| SCHEMBL13080643 | 0.79 | — | — | |
| SCHEMBL19770803 | 0.79 | — | — | |
| SCHEMBL8941385 | 0.79 | — | — | |
| SCHEMBL16945372 | 0.79 | — | — | |
| SCHEMBL3151556 | 0.79 | FAAH (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12486277-B2 | CDK inhibitors and their use as pharmaceuticals | Prelude Therapeutis Incorporated (US) | 2025-12-02 | — | — | US | disclosed |
| EP-4650347-A1 | PHENYL-SUBSTITUTED HETEROARYL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-12473295-B2 | Substituted straight chain spiro derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2025-11-18 | — | — | US | disclosed |
| US-20250333421-A1 | PYRIDAZINES OR 1,2,4-TRIAZINES SUBSTITUTED BY SPIROCYCLIC AMINES | JANSSEN PHARMACEUTICA NV (BE) | 2025-10-30 | — | — | US | disclosed |
| WO-2025224759-A1 | INDANOL SUBSTITUTED DIAMINO PYRIMIDINE CARBOXAMIDES AS DUAL ATM/DNA-PK INHIBITORS | BUGWORKS RESEARCH INDIA PVT. LTD (IN) | 2025-10-30 | — | — | WO | disclosed |
| US-20250326764-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS LLC (US) | 2025-10-23 | — | — | US | disclosed |
| US-12435068-B2 | Anthelmintic compounds | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| US-20250289801-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-09-18 | — | — | US | disclosed |
| US-12312359-B2 | Inhibitors of the menin-MLL interaction | VITAE PHARMACEUTICALS, LLC (US) | 2025-05-27 | — | — | US | disclosed |
| CN-115135642-B | Inhibitors of EGFR mutant forms | 缆图药品公司 | 2025-03-04 | — | — | CN | disclosed |
| US-20060052380-A1 | Thieno [2,3,-d]pyridazin-4(5H)-ones; modulation of autoimmune diseases with T-cell antiproliferatives; antiinflammatory; organ transplant rejection; AIDS; chronic obstructive pulmonary disease (COPD); asthma | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | US | disclosed |
| WO-2006018735-A2 | TRIAZOLOPYRIDINE COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2006018727-A2 | TRIAZOLOPYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |
| EP-1587809-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2005-10-26 | — | — | EP | disclosed |
| US-6852726-B2 | Substituted indoles as alpha-1 agonists | SYNTEX LLC (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1501826-A2 | SUBSTITUTED INDOLES AS ALPHA-1 AGONISTS | F. Hoffman-la Roche AG (CH) | 2005-02-02 | — | — | EP | disclosed |
| WO-2004065393-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-08-05 | — | — | WO | disclosed |
| US-20030220319-A1 | Substituted indoles as alpha-1 agonists | SYNTEX (U.S.A.) LLC | 2003-11-27 | — | — | US | disclosed |
| WO-2003064387-A2 | SUBSTITUTED INDOLES AS ALPHA-1 AGONISTS | F. HOFFMAN-LA ROCHE AG (CH) | 2003-08-07 | — | — | WO | disclosed |
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |