Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17957276 | 0.90 | MCHR1 (0.40) | NTRK1NTRK2ALDH1A1PARP1 | |
| SCHEMBL2815670 | 0.88 | NTRK1 (0.40) | NTRK1NTRK2MAPTALDH1A1POLB | |
| SCHEMBL17957241 | 0.88 | MAPT (0.39) | NTRK1NTRK2MAPTALDH1A1ROCK2 | |
| SCHEMBL17957242 | 0.86 | ROCK2 (0.50) | ROCK2ROCK1 | |
| SCHEMBL13133022 | 0.86 | PARP1 (0.41) | NTRK1NTRK2MAPTALDH1A1POLB | |
| SCHEMBL17957277 | 0.85 | NTRK1 (0.39) | NTRK1NTRK2MAPTALDH1A1POLB | |
| SCHEMBL17957281 | 0.85 | MCHR1 (0.43) | NTRK1NTRK2MAPTALDH1A1 | |
| SCHEMBL2814887 | 0.81 | MAPT (0.41) | NTRK1NTRK2MAPTALDH1A1PARP1 | |
| SCHEMBL2815410 | 0.78 | MCHR1 (0.42) | NTRK1NTRK2ALDH1A1PARP1 | |
| SCHEMBL17957284 | 0.78 | NTRK1 (0.42) | NTRK1NTRK2ALDH1A1PARP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193122-B1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-08-03 | — | — | EP | claimed |
| EP-2193122-B1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-08-03 | — | — | EP | disclosed |