Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965095 | 0.92 | S1PR1 (0.56) | MGLLTLR9S1PR1S1PR3HDAC6 | |
| SCHEMBL14242764 | 0.87 | P2RY14 (0.55) | MGLLTLR9P2RY14DGAT1 | |
| SCHEMBL17965061 | 0.86 | NPC1 (0.48) | MGLLS1PR1S1PR3HDAC6HDAC3 | |
| SCHEMBL17964993 | 0.85 | TLR9 (0.43) | MGLLTLR9S1PR1S1PR3HDAC6 | |
| SCHEMBL17965084 | 0.84 | EGLN1 (0.43) | MGLLS1PR1S1PR3HDAC6HDAC3 | |
| SCHEMBL14242824 | 0.83 | S1PR1 (0.54) | MGLLTLR9S1PR1S1PR3HDAC6 | |
| SCHEMBL14707129 | 0.83 | S1PR1 (0.54) | TLR9S1PR1S1PR3HDAC6HDAC3 | |
| SCHEMBL14242828 | 0.79 | P2RY14 (0.55) | S1PR1S1PR3HDAC6HDAC3HDAC1 | |
| SCHEMBL14696380 | 0.78 | S1PR1 (0.49) | TLR9S1PR1S1PR3HDAC6HDAC3 | |
| SCHEMBL17965166 | 0.78 | S1PR1 (0.49) | MGLLTLR9S1PR1S1PR3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | claimed |