Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | UTRN | P46939 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17964993 | 0.93 | TLR9 (0.43) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17965191 | 0.88 | KMT2A (0.38) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17964995 | 0.87 | S1PR1 (0.48) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17965095 | 0.85 | S1PR1 (0.56) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17965196 | 0.85 | S1PR1 (0.45) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17965106 | 0.84 | LMNA (0.40) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL14707129 | 0.81 | S1PR1 (0.54) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL14242824 | 0.79 | S1PR1 (0.54) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL14242828 | 0.79 | P2RY14 (0.55) | S1PR1S1PR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17965048 | 0.78 | GPR119 (0.42) | S1PR1S1PR3HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | claimed |