Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 4/20 | 0.40 |
| ▸ | ARG1 | P05089 | 3/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL28167640 | 0.98 | GSR (0.62) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Gluconic Acid SCHEMBL16193997 | 0.98 | GSR (0.62) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Gluconic Acid SCHEMBL16194000 | 0.98 | GSR (0.62) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Gluconic Acid SCHEMBL28851476 | 0.97 | GSR (0.61) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Gluconic Acid SCHEMBL17965943 | 0.96 | GSR (0.56) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Gluconic Acid SCHEMBL6915249 | 0.95 | GSR (0.59) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Gluconic Acid SCHEMBL27946775 | 0.94 | GSR (0.57) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Sorbitol SCHEMBL4751532 | 0.92 | GSR (0.71) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Galactitol SCHEMBL1167727 | 0.92 | GSR (0.71) | GSRPDE4AUSP2SLCO1B1LMNA | |
| Mannitol SCHEMBL1168590 | 0.92 | GSR (0.71) | GSRPDE4AUSP2SLCO1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053588-A1 | BIOCIDAL RESIN COMPOSITION INCLUDING ONE OR A PLURALITY OF RESINS SELECTED FROM MF, UF, PF, MUF AND PHENOLIC RESINS; AND MORE THAN ONE SOLUBLE COPPER SALT | Améstica Salazar, Luis Alberto (CL) | 2016-08-10 | — | — | EP | disclosed |