Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL28851476 | 0.97 | GSR (0.61) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL6915249 | 0.96 | GSR (0.59) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL28167640 | 0.96 | GSR (0.62) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL16194000 | 0.96 | GSR (0.62) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL16193997 | 0.96 | GSR (0.62) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL28209557 | 0.94 | GSR (0.54) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL17965945 | 0.94 | GSR (0.61) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Mannitol SCHEMBL27929505 | 0.91 | GSR (0.69) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Gluconic Acid SCHEMBL17965943 | 0.90 | GSR (0.56) | GSRPDE4AUSP2SLCO1B1ARG2 | |
| Sorbitol SCHEMBL4751532 | 0.89 | GSR (0.71) | GSRPDE4AUSP2SLCO1B1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103462947-B | Calcium-zinc gluconate granule and method for making thereof | GUIZHOU VIGOUR PHARMACEUTICAL CO., LTD. (CN) | 2015-09-16 | — | — | CN | disclosed |
| CN-103462947-A | Calcium zinc gluconate granules and preparation method thereof | GUIZHOU VIGOUR PHARMACEUTICAL CO LTD | 2013-12-25 | — | — | CN | disclosed |