Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | PIM1 | P11309 | 6/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561284 | 0.90 | MAPT (0.81) | MAPTPIM1PIM3PIM2CHEK1 | |
| SCHEMBL17967635 | 0.79 | MAPT (0.70) | MAPTPIM1PIM3PIM2 | |
| SCHEMBL19269034 | 0.78 | MAPT (0.69) | MAPTPIM1CHEK1ACHE | |
| SCHEMBL17967639 | 0.75 | MAPT (1.00) | MAPTCHEK1TGFBR1 | |
| Hydrochloric Acid SCHEMBL30669792 | 0.74 | MAPT (0.58) | MAPTPIM1PIM3PIM2MET | |
| SCHEMBL17967657 | 0.73 | MAPT (1.00) | MAPT | |
| SCHEMBL18440826 | 0.73 | CLK2 (0.70) | MAPTPIM1PIM3PIM2CLK2 | |
| SCHEMBL12666733 | 0.73 | CHEK1 (0.69) | MAPTPIM1PIM3PIM2CHEK1 | |
| SCHEMBL17592016 | 0.72 | PIM1 (0.65) | MAPTPIM1PIM3PIM2CLK2 | |
| SCHEMBL17967653 | 0.72 | MAPT (1.00) | MAPTMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253762-B1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-05-05 | — | — | EP | claimed |
| WO-2016124508-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-11 | — | — | WO | claimed |
| EP-3253762-B1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-05-05 | — | — | EP | disclosed |
| WO-2016124508-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-11 | — | — | WO | disclosed |