SCHEMBL17969656

SCHEMBL17969656

CN(C)c1ccc2cccc(N(C)C)c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.65
KDM4E B2RXH2 2/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
TERT O14746 1/20 0.45
APP P05067 1/20 0.45
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
SIGMAR1 Q99720 2/20 0.40
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 1/20 0.39
NSD2 O96028 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
CHEK1 O14757 1/20 0.38
NEK2 P51955 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20516077 0.85 MCL1 (0.53) MCL1KDM4EGAAMAPTTERT
SCHEMBL2025062 0.84 MCL1 (0.50) MCL1KDM4EGAAMAPTTERT
SCHEMBL17383662 0.80 CYP1A2 (0.59) MCL1KDM4ETERTAPPALDH1A1
SCHEMBL23183323 0.79 ALDH1A1 (0.56) MCL1KDM4EMAPTTERTAPP
SCHEMBL5487330 0.79 MCL1 (0.62) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL29349880 0.78 MCL1 (1.00) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL4076470 0.78 F2 (0.49) MCL1KDM4EGAAMAPTTERT
SCHEMBL5697319 0.78 CTDSP1 (0.53) MCL1KDM4EGAAMAPTTERT
SCHEMBL31232554 0.78 APP (0.44) MCL1KDM4EGAAMAPTTERT
SCHEMBL26128475 0.78 APP (0.44) MCL1KDM4EGAAMAPTTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160233546-A1 ELECTROLYTE SOLUTION AND LITHIUM ION BATTERIES USING THE SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2016-08-11 US claimed
US-20160233546-A1 ELECTROLYTE SOLUTION AND LITHIUM ION BATTERIES USING THE SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2016-08-11 US disclosed