SCHEMBL17973751

SCHEMBL17973751

CCC(C)c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 1/20 0.45
PTGS2 P35354 1/20 0.43
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
CYP2C9 P11712 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
CYP17A1 P05093 1/20 0.40
TRPA1 O75762 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12299149 1.00 GRIA4 (0.45) GRIA4PTGS2CHRNB2CHRNA4CYP2C9
SCHEMBL23542270 1.00 GRIA4 (0.45) GRIA4PTGS2CHRNB2CHRNA4CYP2C9
SCHEMBL12299141 0.98 GRIA4 (0.44) GRIA4PTGS2CHRNB2CHRNA4CYP2C9
SCHEMBL17973753 0.98 GRIA4 (0.44) GRIA4PTGS2CHRNB2CHRNA4CYP2C9
SCHEMBL12299061 0.98 GRIA4 (0.44) GRIA4PTGS2CHRNB2CHRNA4CYP2C9
SCHEMBL12299068 0.98 GRIA4 (0.44) GRIA4PTGS2CHRNB2CHRNA4CYP2C9
SCHEMBL12299146 0.96 GRIA4 (0.41) GRIA4PTGS2CYP2C9ALDH1A1TSHR
SCHEMBL8531958 0.96 GRIA4 (0.41) GRIA4PTGS2CYP2C9ALDH1A1TSHR
SCHEMBL13027935 0.93 PTGS2 (0.42) GRIA4PTGS2CHRNB2CHRNA4CYP17A1
SCHEMBL13027938 0.93 PTGS2 (0.42) GRIA4PTGS2CHRNB2CHRNA4CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225998-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-08-04 US disclosed