SCHEMBL17974475

SCHEMBL17974475

CC(=O)Nc1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNASE1L3 Q13609 1/20 0.68
PRMT1 Q99873 1/20 0.68
USP2 O75604 3/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
CA9 Q16790 15/20 0.60
CA1 P00915 13/20 0.60
CA2 P00918 13/20 0.60
CA12 O43570 5/20 0.58
MEN1 O00255 2/20 0.57
POLB P06746 2/20 0.57
KMT2A Q03164 2/20 0.57
ALPL P05186 1/20 0.57
ALPI P09923 1/20 0.57
ALPG P10696 1/20 0.57
ATM Q13315 1/20 0.55
PLEC Q15149 1/20 0.55
CA14 Q9ULX7 2/20 0.55
CA7 P43166 2/20 0.53
PTGER3 P43115 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17974603 0.92 DNASE1L3 (0.66) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL17971015 0.89 DNASE1L3 (0.65) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL609275 0.89 DNASE1L3 (0.65) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL23205535 0.88 DNASE1L3 (0.63) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL17971092 0.88 DNASE1L3 (0.63) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL24454976 0.87 DNASE1L3 (0.65) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL12061907 0.87 USP2 (0.66) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL17970978 0.87 DNASE1L3 (0.64) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL12231957 0.85 CA9 (0.72) DNASE1L3PRMT1USP2L3MBTL1CA9
SCHEMBL12045940 0.84 USP2 (0.68) DNASE1L3PRMT1USP2L3MBTL1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160221992-A1 DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2016-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160221992-A1 DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF MSR1, CD74, CD4 DNASE1L3 131/4885PRMT1 719/4885USP2 3447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.