Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668221 | 1.00 | EPHX1 (0.52) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL681375 | 0.97 | EPHX1 (0.55) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL22856487 | 0.95 | EPHX1 (0.52) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL13997666 | 0.93 | EPHX1 (0.56) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL2599824 | 0.90 | EPHX1 (0.59) | EPHX1TSHRMAPTMEN1THRB | |
| SCHEMBL23267022 | 0.90 | EPHX1 (0.46) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL20231880 | 0.90 | TSHR (0.48) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL23267823 | 0.90 | EPHX1 (0.46) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL14448265 | 0.90 | TSHR (0.48) | EPHX1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL20231881 | 0.90 | TSHR (0.48) | EPHX1TSHRCYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | MSR1, CD74, CD4 | EPHX1 2264/4885TSHR 1795/4885CYP3A4 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.