Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571936 | 1.00 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL16970388 | 0.87 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL17976903 | 0.87 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL15572463 | 0.86 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL17976883 | 0.86 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL16970294 | 0.84 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL16970297 | 0.84 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL15571318 | 0.83 | HRH3 (0.47) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL17976916 | 0.83 | HRH3 (0.47) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL15570528 | 0.82 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888243-B1 | ACRYLAMIDE COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2016-08-17 | — | — | EP | claimed |