Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571272 | 0.82 | HRH3 (0.49) | HRH3KCNH2MEN1KMT2A | |
| SCHEMBL17976901 | 0.82 | HRH3 (0.49) | HRH3KCNH2MEN1KMT2A | |
| SCHEMBL2004014 | 0.79 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL2008698 | 0.76 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL17976916 | 0.73 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL15571318 | 0.73 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL12485580 | 0.71 | HRH3 (0.72) | HRH3 | |
| SCHEMBL738339 | 0.69 | HRH3 (0.57) | HRH3KCNH2 | |
| SCHEMBL2005954 | 0.69 | HRH3 (0.57) | HRH3KCNH2 | |
| SCHEMBL16702162 | 0.69 | NAMPT (0.45) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888243-B1 | ACRYLAMIDE COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2016-08-17 | — | — | EP | disclosed |