Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GPR183 | P32249 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571272 | 1.00 | HRH3 (0.49) | HRH3KCNH2MEN1KMT2AGPR183 | |
| SCHEMBL17976916 | 0.91 | HRH3 (0.47) | HRH3KCNH2GPR183ALDH1A1NPC1 | |
| SCHEMBL15571318 | 0.91 | HRH3 (0.47) | HRH3KCNH2GPR183ALDH1A1NPC1 | |
| SCHEMBL17976879 | 0.84 | HRH3 (0.53) | HRH3MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17976880 | 0.84 | HRH3 (0.53) | HRH3MEN1KMT2AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL15572697 | 0.83 | HRH3 (0.53) | HRH3MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17976909 | 0.82 | HRH3 (0.46) | HRH3KCNH2MEN1KMT2A | |
| SCHEMBL2004014 | 0.81 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL15572648 | 0.78 | ALDH1A1 (0.67) | KMT2AALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL17976873 | 0.78 | ALDH1A1 (0.67) | KMT2AALDH1A1L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888243-B1 | ACRYLAMIDE COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2016-08-17 | — | — | EP | claimed |