Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.86 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17977532 | 0.93 | RORC (1.00) | RORCRARGPPARG | |
| SCHEMBL17977577 | 0.89 | RORC (0.88) | RORCRARGPPARG | |
| SCHEMBL17977607 | 0.89 | RORC (0.70) | RORCRARGPPARG | |
| SCHEMBL17978072 | 0.89 | RORC (0.88) | RORCRARGPPARG | |
| SCHEMBL17977890 | 0.85 | RORC (0.81) | RORCPPARG | |
| SCHEMBL17977741 | 0.85 | RORC (0.78) | RORC | |
| SCHEMBL18019663 | 0.84 | RORC (0.80) | RORCPPARG | |
| SCHEMBL17978374 | 0.84 | RORC (0.80) | RORCRARGPPARG | |
| SCHEMBL18019631 | 0.83 | RORC (0.78) | RORCPPARG | |
| SCHEMBL18019754 | 0.83 | RORC (0.62) | RORCRARGPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128908-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2016-08-18 | — | — | WO | claimed |
| WO-2016128908-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2016-08-18 | — | — | WO | disclosed |