Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043848 | 0.88 | POLB (0.46) | POLBLMNANR3C2RXFP1CXCR4 | |
| SCHEMBL17979430 | 0.87 | POLB (0.43) | POLBLMNANR3C2RXFP1CXCR4 | |
| SCHEMBL21043796 | 0.86 | POLB (0.45) | POLBLMNANR3C2RXFP1CXCR4 | |
| SCHEMBL17979407 | 0.85 | POLB (0.42) | POLBLMNANR3C2RXFP1CXCR4 | |
| SCHEMBL17979556 | 0.84 | POLB (0.43) | POLBLMNANR3C2RXFP1CXCR4 | |
| SCHEMBL17979478 | 0.82 | LMNA (0.49) | POLBLMNARXFP1KMT2ATP53 | |
| SCHEMBL19865860 | 0.81 | POLB (0.38) | POLBLMNARXFP1HDAC6MAPT | |
| SCHEMBL17979349 | 0.80 | KMT2A (0.44) | POLBLMNANR3C2RXFP1CXCR4 | |
| SCHEMBL21043832 | 0.77 | POLB (0.48) | POLBLMNANR3C2RXFP1HDAC6 | |
| SCHEMBL21043781 | 0.75 | POLB (0.46) | POLBLMNANR3C2RXFP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| EP-3256447-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128317-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |