Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G6 | O60733 | 2/20 | 0.91 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.91 |
| ▸ | FASN | P49327 | 1/20 | 0.59 |
| ▸ | LYPLA1 | O75608 | 2/20 | 0.47 |
| ▸ | LYPLA2 | O95372 | 2/20 | 0.47 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979639 | 0.95 | PLA2G6 (1.00) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL17979630 | 0.90 | PLA2G6 (0.80) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL19514904 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL17760808 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL17760804 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL19514903 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL19514898 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL19514935 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL19514905 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 | |
| SCHEMBL19514899 | 0.87 | PLA2G6 (0.84) | PLA2G6PLA2G4AFASNLYPLA1LYPLA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128131-A1 | BETA-LACTONE INHIBITORS OF PHOSPHOLIPASE A2 AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-08-18 | — | — | WO | claimed |
| WO-2016128131-A1 | BETA-LACTONE INHIBITORS OF PHOSPHOLIPASE A2 AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-08-18 | — | — | WO | disclosed |
| WO-2016128131-A1 | BETA-LACTONE INHIBITORS OF PHOSPHOLIPASE A2 AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-08-18 | — | — | WO | disclosed |