Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 2/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17980318 | 0.95 | KDM1A (0.55) | OPRM1EPHA2KDM1AMAOBKDM5A | |
| SCHEMBL29663605 | 0.92 | NMUR2 (0.55) | OPRM1EPHA2KDM1ANMUR2NMUR1 | |
| SCHEMBL31119895 | 0.92 | NMUR2 (0.60) | OPRM1EPHA2NMUR2NMUR1CXCR4 | |
| SCHEMBL30556351 | 0.92 | NMUR2 (0.60) | OPRM1EPHA2NMUR2NMUR1CXCR4 | |
| SCHEMBL31692757 | 0.90 | NTSR2 (0.53) | OPRM1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30556353 | 0.90 | F2 (0.56) | OPRM1NMUR2NMUR1MAPK8MAPK9 | |
| SCHEMBL30479459 | 0.90 | NMUR2 (0.53) | OPRM1EPHA2NMUR2NMUR1NPY1R | |
| SCHEMBL29821642 | 0.89 | EPHA2 (0.59) | OPRM1EPHA2NMUR2NMUR1NPY1R | |
| SCHEMBL30772917 | 0.89 | OPRM1 (0.58) | OPRM1EPHA2NMUR2NMUR1 | |
| SCHEMBL29864848 | 0.88 | OPRM1 (0.57) | OPRM1EPHA2NMUR2NMUR1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222084-A1 | Compositions Comprising D-Amino Acid Peptides and Methods of Production and Use Thereof for Inhibiting Autoantibodies | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2016-08-04 | — | — | US | disclosed |