SCHEMBL17983232

SCHEMBL17983232

CC(CN1C(=O)C2CCCC2C1=O)C1CO1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.32
PIK3CD O00329 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17983146 0.97 ALDH1A1 (0.39) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17983338 0.81 ALDH1A1 (0.34) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17983051 0.79 ALDH1A1 (0.35) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL8282190 0.78 PIK3CD (0.44) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17983116 0.78 ALDH1A1 (0.34) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17983212 0.78 ALDH1A1 (0.37) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17983078 0.75 ALDH1A1 (0.38) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17983339 0.75 PIK3CD (0.36) PIK3CD
SCHEMBL17983083 0.74 ALDH1A1 (0.37) ALDH1A1KDM4ELMNARAB9ATDP1
SCHEMBL17532417 0.74 ALDH1A1 (0.42) ALDH1A1KDM4ELMNARAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9540463-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2017-01-10 US claimed
US-20160237186-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-08-18 US claimed
US-9540463-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2017-01-10 US disclosed
US-20160237186-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed