Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295472 | 0.82 | CHRM2 (0.62) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL230222 | 0.82 | CHRM2 (0.70) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL29438821 | 0.82 | CHRM2 (0.70) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL28932276 | 0.81 | CHRM2 (0.56) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL1496459 | 0.81 | SMN1; SMN2 (0.58) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL25211342 | 0.80 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL18493706 | 0.80 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| Zinc Ion SCHEMBL30442739 | 0.80 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL317984 | 0.80 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 | |
| Zinc Ion SCHEMBL30205248 | 0.80 | CHRM2 (0.68) | CHRM2MAOAMAOBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4563146-A1 | FLAVIVIRUS INHIBITORS | IRBM S.P.A. (IT) | 2025-06-04 | — | — | EP | disclosed |
| US-20160237037-A1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES, INC. | 2016-08-18 | — | — | US | disclosed |
| CN-101652354-B | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG | 2014-06-18 | — | — | CN | disclosed |
| CN-101652354-A | insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG DE | 2010-02-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237037-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM1A, KDM3A | CHRM2 3004/4885MAOA 1678/4885MAOB 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.