SCHEMBL230222

SCHEMBL230222

c1ccc(CNCc2ccccn2)nc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.70
MAOA P21397 2/20 0.63
MAOB P27338 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.61
KDM4E B2RXH2 3/20 0.59
L3MBTL1 Q9Y468 4/20 0.56
ALDH1A1 P00352 3/20 0.56
SIRT2 Q8IXJ6 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
SCN8A Q9UQD0 1/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
HRH1 P35367 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438821 1.00 CHRM2 (0.70) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL18493706 0.98 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
Zinc Ion SCHEMBL30205248 0.98 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL317984 0.98 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
Zinc Ion SCHEMBL30442739 0.98 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL25211342 0.98 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL9777455 0.91 CHRM2 (0.61) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL5569292 0.91 L3MBTL1 (0.62) CHRM2MAOAMAOBSMN1; SMN2KDM4E
Pyridine SCHEMBL4753513 0.91 CHRM2 (0.61) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL3314110 0.91 L3MBTL1 (0.62) CHRM2MAOAMAOBSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2588 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4732029-A1 METHODS FOR MAGNETIC RESONANCE MOLECULAR IMAGING OF NANOCONSTRUCTS AND USES THEREOF Regents of the University of Michigan (US) 2026-04-29 EP claimed
EP-4263861-B1 COLORIMERIC METHOD FOR DETECTION OF AMPLIFIED GENETIC MATERIAL AND USES THEREOF UNIV NOVA DE LISBOA (PT) 2026-04-08 EP claimed
EP-4706724-A2 GAS DELIVERY DEVICES The Regents Of The University Of Michigan (US) 2026-03-11 EP claimed
US-20260035766-A1 PROCESS AND SYSTEM FOR RECOVERING COPPER AND COBALT FROM SULFIDIC MATERIALS CAPSTONE COPPER CORP D/B/A CAPSTONE COPPER (CA) 2026-02-05 US claimed
US-20260027227-A1 NOVEL THIOL REDUCTANT, METHOD AND USE THEREOF SUZHOU BIOREINNO BIOTECHNOLOGY LTD COMPANY (CN) 2026-01-29 US claimed
EP-3609552-B1 GAS DELIVERY DEVICES UNIV MICHIGAN REGENTS (US) 2025-12-10 EP claimed
US-12473250-B2 Molecular design of new antibiotics and antibiotic adjuvants against MCR strains SINGAPORE HEALTH SERVICES PTE LTD (SG) 2025-11-18 US claimed
US-20250326775-A1 A NOVEL THIOL REDUCTANT, PREPARATION METHOD AND USE THEREOF SUZHOU BIOREINNO BIOTECHNOLOGY LTD COMPANY (CN) 2025-10-23 US claimed
WO-2025217208-A1 CHEMICAL MECHANICAL PLANARIZATION POLISHING FOR INTERCONNECTS DIFFUSION BARRIER MATERIALS VERSUM MATERIALS US, LLC (US) 2025-10-16 WO claimed
US-20250296078-A1 TREATING WASTE STREAMS WITH ADVANCED SEPARATION TECHNOLOGIES NEW MATTOCK RESOURCES, INC. (US) 2025-09-25 US claimed
US-5178746-A Contacting with ion exchange resin containing picolylamine group BIO-RECOVERY SYSTEMS, INC. (US) 1993-01-12 US claimed
EP-0507467-A1 Resins having improved exchange kinetics THE DOW CHEMICAL COMPANY (US) 1992-10-07 EP claimed
US-5141965-A Resins having improved exchange kinetics THE DOW CHEMICAL COMPANY (US) 1992-08-25 US claimed
US-5102640-A Demetallization by complexing with silicate particles having ligands on their surfaces SCHLAPFER CARL W (CH) 1992-04-07 US claimed
US-4666683-A WATER INSOLUBLE ION EXCHANGE RESIN ECO-TEC LIMITED (CA) 1987-05-19 US claimed
US-4320099-A Process for nickel removal from concentrated aqueous cobaltous sulfate solutions INCO LIMITED (CA) 1982-03-16 US claimed
US-4274930-A Process for recovering cobalt electrolytically THE INTERNATIONAL NICKEL COMPANY, INC. (US) 1981-06-23 US claimed
US-4246350-A MADE FROM STYRENE-DIVINYLBENZENE COPOLYMER WITH REOCCURING UNITS OF BIS-PICOLYLAMINE, IMINO DIACETATE AND HYDROXYETHYL PICOLYLAMINE THE DOW CHEMICAL COMPANY (US) 1981-01-20 US claimed
US-4153605-A Process for preparing bispicolylamine THE DOW CHEMICAL COMPANY (US) 1979-05-08 US claimed
US-4080338-A REACTING CYANOPYRIDINE WITH HYDROGEN, PALLADIUM CATALYST THE DOW CHEMICAL COMPANY (US) 1978-03-21 US claimed