SCHEMBL17986296

SCHEMBL17986296

CCC/[C]=N\Oc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.37
CA4 P22748 1/20 0.34
CHRNB2 P17787 2/20 0.32
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNA7 P36544 2/20 0.32
CHRNA4 P43681 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNA3 P22001 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17986297 1.00 LTA4H (0.37) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL17986340 0.89 LTA4H (0.43) LTA4HMEN1KMT2AKCNA3MAPT
SCHEMBL17986339 0.89 LTA4H (0.43) LTA4HMEN1KMT2AKCNA3MAPT
SCHEMBL17986234 0.83 LTA4H (0.38) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL17986235 0.83 LTA4H (0.38) LTA4HCA4CHRNB2CHRNB4CHRNA3
SCHEMBL5958244 0.73 TSHR (0.40) TSHRMAPTL3MBTL1
SCHEMBL5958246 0.73 TSHR (0.40) TSHRMAPTL3MBTL1
SCHEMBL7363159 0.73 LTA4H (0.45) LTA4HCA4KCNA3TSHRL3MBTL1
SCHEMBL4151571 0.72 CA4 (0.42) LTA4HCA4KCNA3TSHRL3MBTL1
SCHEMBL4151573 0.72 CA4 (0.42) LTA4HCA4KCNA3TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9635857-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-02 US disclosed
US-20160235065-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160235065-A1 TETRAZOLINONE COMPOUND AND USE THEREOF MRPS17, TAOK1, TAOK3 LTA4H 1589/4885CA4 1953/4885CHRNB2 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.