Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273731 | 0.89 | FOLH1 (0.49) | PTGS1PTGS2FNTAFNTBFOLH1 | |
| SCHEMBL15919123 | 0.89 | FOLH1 (0.49) | PTGS1PTGS2FNTAFNTBFOLH1 | |
| SCHEMBL24141118 | 0.87 | HPGDS (0.47) | MMP12MMP2MMP8PTGS1PTGS2 | |
| SCHEMBL9363327 | 0.84 | HPGDS (0.43) | PTGS1PTGS2HPGDSFNTAFNTB | |
| SCHEMBL17775702 | 0.84 | PTGS1 (0.54) | MMP12MMP2MMP8PTGS1PTGS2 | |
| SCHEMBL11932161 | 0.82 | PTGS1 (0.38) | MMP12MMP2MMP8PTGS1PTGS2 | |
| SCHEMBL19429720 | 0.82 | ALB (0.47) | PTGS1PTGS2NOD1NPFFR1 | |
| SCHEMBL16156903 | 0.81 | PTGS1 (0.53) | PTGS1PTGS2NOD1FOLH1RIMKLA | |
| SCHEMBL31047765 | 0.80 | PTGS1 (0.49) | PTGS1PTGS2NOD1 | |
| SCHEMBL23953334 | 0.80 | PTGS1 (0.43) | MMP12MMP2MMP8PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220707-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | AVELAS ACQUISITION CORPORATION | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220707-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | SLC7A1, SLC47A1, SLC47A2 | MMP12 203/4885MMP2 275/4885MMP8 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.