Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.59 |
| ▸ | HTR2B | P41595 | 12/20 | 0.59 |
| ▸ | HTR2A | P28223 | 11/20 | 0.59 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986442 | 0.90 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL17986367 | 0.89 | HTR2A (0.61) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL17986694 | 0.89 | HTR2C (0.61) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL17986443 | 0.88 | HTR2C (0.51) | HTR2CHTR2BHTR2A | |
| SCHEMBL17985452 | 0.88 | HTR2C (0.63) | HTR2CHTR2BHTR2A | |
| SCHEMBL17986692 | 0.86 | HTR2C (0.63) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL17985453 | 0.86 | HTR2C (0.41) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL17962731 | 0.85 | HTR2C (0.62) | HTR2CHTR2BHTR2A | |
| SCHEMBL17986423 | 0.82 | HTR2A (0.60) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL30368732 | 0.80 | HTR2C (0.62) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250549-B1 | CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS | UNIV ILLINOIS (US) | 2021-06-23 | — | — | EP | disclosed |
| CN-107810175-B | Cyclopropylmethylamines as selective 5-HT (2C) receptor agonists | 伊利诺伊大学评议会 | 2021-06-15 | — | — | CN | disclosed |
| US-10407381-B2 | Cyclopropylmethanamines as selective 5-HT(2C) receptor agonists | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-09-10 | — | — | US | disclosed |
| CN-107810175-A | The alternatively cyclopropyl-methylamine of the HT of property 5 (2C) receptor stimulating agent | 伊利诺伊大学评议会 | 2018-03-16 | — | — | CN | disclosed |
| WO-2016123164-A1 | CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407381-B2 | Cyclopropylmethanamines as selective 5-HT(2C) receptor agonists | HTR2C, HTR2A, HTR1A | HTR2C 1/4885HTR2B 10/4885HTR2A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.