Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15558650 | 0.75 | GSK3A (0.39) | GPR139GSK3AGSK3BGAA | |
| SCHEMBL17986919 | 0.73 | PIK3CD (0.31) | GSK3B | |
| SCHEMBL17986819 | 0.68 | — | — | |
| SCHEMBL15559317 | 0.67 | PIK3CD (0.46) | — | |
| SCHEMBL15613325 | 0.66 | PIK3CD (0.39) | — | |
| SCHEMBL24003499 | 0.65 | CHRM2 (0.39) | GAA | |
| SCHEMBL30238788 | 0.65 | CHRM2 (0.39) | GAA | |
| SCHEMBL19421494 | 0.65 | CHRM2 (0.39) | GAA | |
| SCHEMBL12710431 | 0.65 | CHRM2 (0.39) | GAA | |
| SCHEMBL15558772 | 0.65 | BAZ2B (0.39) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016119707-A1 | NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-08-04 | — | — | WO | disclosed |