Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15598612 | 0.80 | KDM4E (0.39) | GSK3B | |
| SCHEMBL15598610 | 0.78 | GSK3B (0.34) | PIK3CDPIK3CGPIK3R1GSK3B | |
| SCHEMBL15550320 | 0.78 | GSK3B (0.34) | PIK3CDPIK3CGPIK3R1GSK3B | |
| SCHEMBL15558529 | 0.78 | COMT (0.36) | PIK3CDPIK3CGPIK3R1GSK3B | |
| SCHEMBL15598613 | 0.78 | GSK3B (0.34) | PIK3CDPIK3CGPIK3R1GSK3B | |
| SCHEMBL17986923 | 0.73 | GPR139 (0.33) | GSK3B | |
| SCHEMBL17174856 | 0.73 | PIK3CD (0.42) | PIK3CDPIK3CGPIK3R1 | |
| SCHEMBL15559495 | 0.72 | ALDH1A1 (0.39) | GSK3B | |
| SCHEMBL15559028 | 0.72 | GSK3A (0.30) | GSK3B | |
| SCHEMBL15598475 | 0.72 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016119707-A1 | NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-08-04 | — | — | WO | disclosed |