SCHEMBL179872

SCHEMBL179872

O=C(O)/C=C/c1cc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.58
MAPT P10636 2/20 0.55
IDO1 P14902 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP2C19 P33261 1/20 0.55
ATP6V1B1 P15313 1/20 0.52
KDM4E B2RXH2 1/20 0.51
DAO P14920 1/20 0.51
HPGD P15428 1/20 0.51
SRD5A2 P31213 1/20 0.51
HSD17B10 Q99714 1/20 0.51
FLT3 P36888 1/20 0.49
BCHE P06276 1/20 0.48
ACHE P22303 1/20 0.48
ESR1 P03372 1/20 0.47
RAB9A P51151 1/20 0.46
HDAC3 O15379 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245110 1.00 CYP2A6 (0.58) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL29455098 1.00 CYP2A6 (0.58) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL30640889 1.00 CYP2A6 (0.58) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL6822742 0.87 MAPT (0.55) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL6822744 0.87 MAPT (0.55) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL7646521 0.86 MAPT (0.61) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL3220717 0.85 CYP2A6 (0.56) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL3220733 0.85 CYP2A6 (0.56) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL13229465 0.85 CYP2A6 (0.56) CYP2A6MAPTIDO1NPSR1CYP1A2
SCHEMBL31447975 0.85 CYP2A6 (0.56) CYP2A6MAPTIDO1NPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5674678-A Process for controlling cultures of recombinants HITACHI, LTD. (JP) 1997-10-07 US claimed
EP-0458437-B1 Process for production of human nerve growth factor by genetic engineering HITACHI LTD (JP) 1996-10-09 EP claimed
EP-0335400-B1 Processes for production of human epidermal growth factor by genetic engineering HITACHI LTD (JP) 1994-06-08 EP claimed
US-5139938-A PRODUCTION OF SUBSTANCES WITH AN ACETIC ACID-PRODUCING AND ASSIMILATING BACTERIUM INHIBITED BY ACETIC ACID HITACHI, LTD. (JP) 1992-08-18 US claimed
EP-0283726-B1 METHOD FOR CULTIVATION WITH ACETATE CONCENTRATION MONITORING AND APPARATUS FOR THE SAME HITACHI, LTD. (JP) 1992-06-03 EP claimed
EP-0165613-B1 PROCESS FOR CONTROLLING CULTURE OF RECOMBINANTS HITACHI, LTD. (JP) 1992-01-15 EP claimed
EP-0152483-B1 PROCESS FOR PRODUCING PEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-03-29 EP claimed
EP-0283726-A1 Method for cultivation with acetate concentration monitoring and apparatus for the same HITACHI, LTD. (JP) 1988-09-28 EP claimed
US-4746608-A INTERFERON BY FERMENTATION; ADDING 3-INDOLYLACRYLIC ACID KYOWA HAKKO KOGYO CO., LTD. (JP) 1988-05-24 US claimed
EP-0152483-A1 PROCESS FOR PRODUCING PEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 1985-08-28 EP claimed
JP-9067340-A None JP disclosed
CN-111684565-B Mass spectrometry device and mass correction method for mass spectrometry device 株式会社岛津制作所 2024-11-05 CN disclosed
CN-118526525-A Application of Bifidobacterium longum subspecies infantis NKU FB 3-14 and metagen preparation thereof in anti-aging and anti-systemic chronic inflammation 天赋能(天津)功能食品研究发展有限公司 2024-08-23 CN disclosed
US-20240229050-A9 SEMI-RATIONAL GENOME EVOLUTION ENGINEERING METHOD FOR PLANTS NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2024-07-11 US disclosed
WO-2024135827-A1 NEW PSORALEN COMPOUND 国立大学法人 長崎大学 2024-06-27 WO disclosed
EP-0102634-A1 Recombinant DNA, microorganism transformed therewith and use thereof Takeda Chemical Industries, Ltd. (JP) 1984-03-14 EP disclosed
EP-0020147-B1 A DNA TRANSFER VECTOR FOR HUMAN PRE-GROWTH HORMONE, A MICROORGANISM TRANSFORMED THEREBY, AND A METHOD OF CLONING THEREFOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-01-25 EP disclosed
EP-0046669-A1 Somatostatin or somatostatin precursors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1982-03-03 EP disclosed
EP-0020147-A1 A DNA transfer vector for human pre-growth hormone, a microorganism transformed thereby, and a method of cloning therefor THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1980-12-10 EP disclosed
EP-0020251-A2 DNA transfer vector, host transformed with it, vaccine, and their production THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1980-12-10 EP disclosed