Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.68 |
| ▸ | CA1 | P00915 | 7/20 | 0.68 |
| ▸ | CA2 | P00918 | 7/20 | 0.68 |
| ▸ | CA9 | Q16790 | 7/20 | 0.68 |
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439584 | 0.99 | CA1 (0.67) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL9965358 | 0.95 | CA1 (0.67) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL17974334 | 0.91 | CA12 (0.66) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL12709532 | 0.88 | CA1 (0.70) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL12461819 | 0.88 | CA12 (0.67) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL30440104 | 0.87 | CA1 (0.66) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL1541945 | 0.86 | CA1 (0.64) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL25028474 | 0.85 | CA12 (0.70) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL17960695 | 0.85 | CA12 (0.70) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL24142767 | 0.85 | CA12 (0.57) | CA12CA1CA2CA9SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968233-B2 | Monothiol mucolytic agents | PARION SCIENCES, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. | 2019-01-31 | — | — | US | disclosed |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2016123335-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968233-B2 | Monothiol mucolytic agents | MUC1, HRH2, MAN2A1 | CA12 513/4885CA1 1466/4885CA2 2413/4885 |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | CA12 588/4885CA1 1786/4885CA2 2639/4885 |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | CA12 588/4885CA1 1786/4885CA2 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.