SCHEMBL17989347

SCHEMBL17989347

c1ccc2cc3c(cc2c1)c1ccccc1n3-c1nc2ccccc2s1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KAT2A Q92830 1/20 0.46
KAT2B Q92831 1/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 2/20 0.43
MAPK1 P28482 1/20 0.43
NPC1 O15118 5/20 0.41
RAB9A P51151 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 3/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 2/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17990193 0.92 KDM4E (0.44) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17245510 0.92 KDM4E (0.44) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17990190 0.91 KDM4E (0.43) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL16484373 0.89 KAT2A (0.54) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17990176 0.89 KDM4E (0.46) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17990191 0.87 LMNA (0.39) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17246603 0.87 TP53 (0.42) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17228178 0.86 KDM4E (0.49) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17246498 0.85 KAT2A (0.43) TP53HSD17B10KAT2AKAT2BMEN1
SCHEMBL17246297 0.85 KAT2A (0.43) TP53HSD17B10KAT2AKAT2BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed