SCHEMBL17989449

SCHEMBL17989449

CC1(C)c2cc3ccccc3cc2-c2ccc3c4ccccc4n(-c4ccc5oc6ccccc6c5c4)c3c21

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGER4 P35408 1/20 0.32
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16940894 0.91 KDM4E (0.33) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL18058184 0.89 NCOA1 (0.34) NPC1MAPT
SCHEMBL15462314 0.89 PTGER4 (0.33) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL17989458 0.88 SIRT2 (0.33) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL18058198 0.87 NCOA1 (0.32) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL17989448 0.86 SIRT2 (0.31) PTGER4
SCHEMBL17988923 0.86 ALDH1A1 (0.33) ALDH1A1HPGDRAB9AKMT2A
SCHEMBL18058186 0.86
SCHEMBL18488977 0.85 MAPT (0.35) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL17989557 0.85 KDM4E (0.38) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed