SCHEMBL17990352

SCHEMBL17990352

c1ccc(-n2c3ccccc3c3c(-n4c5ccccc5c5ccc6c(c7ccc8ccccc8c7n6-c6ccccc6)c54)cccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
JAK2 O60674 1/20 0.30
JAK3 P52333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17990360 0.94 KDM4E (0.42) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL17989804 0.92 KDM4E (0.44) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL17990351 0.91 KDM4E (0.42) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL17989775 0.91 L3MBTL1 (0.50) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL17990341 0.90 ATM (0.47) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL25098441 0.90 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A1SIGMAR1
SCHEMBL26472547 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL19342676 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL19769683 0.89 L3MBTL1 (0.56) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL17245387 0.88 KDM4E (0.51) KDM4EATML3MBTL1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed