SCHEMBL17990482

SCHEMBL17990482

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc(-n4c5ccccc5c5cc6c(cc54)c4cc5ccccc5cc4n6-c4ccccc4)cc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ATM Q13315 1/20 0.53
HDAC4 P56524 1/20 0.40
KMT2A Q03164 4/20 0.38
IL1R1 P14778 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 3/20 0.38
HTR6 P50406 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 1/20 0.38
PTPN1 P18031 1/20 0.36
TSHR P16473 2/20 0.36
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
KDR P35968 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17689857 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17943726 0.97 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL12414463 0.97 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17990484 0.96 L3MBTL1 (0.51) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL21709013 0.94 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17990412 0.94 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17990462 0.94 L3MBTL1 (0.56) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL22186704 0.93 L3MBTL1 (0.55) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17228227 0.92 L3MBTL1 (0.62) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL26154773 0.91 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed