SCHEMBL17990490

SCHEMBL17990490

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc(-n4c5ccccc5c5cc6c7ccc8ccccc8c7n(-c7ccccc7)c6cc54)cc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
HDAC4 P56524 1/20 0.36
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
PRSS1 P07477 1/20 0.34
KMT2A Q03164 3/20 0.34
IL1R1 P14778 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
TSHR P16473 2/20 0.31
SIGMAR1 Q99720 1/20 0.31
HTR6 P50406 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22186449 0.97 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL22186434 0.97 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL17990495 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL21366680 0.96 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL17990426 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL27453870 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL17943387 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL22869041 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL22926972 0.91 KDM4E (0.44) L3MBTL1KDM4EATMHDAC4F2
SCHEMBL22186450 0.91 KDM4E (0.44) L3MBTL1KDM4EATMHDAC4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed