Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.81 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.81 |
| ▸ | SSTR5 | P35346 | 7/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.39 |
| ▸ | TERF2IP | Q9NYB0 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335248 | 1.00 | KDM1A (0.81) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL17992335 | 0.97 | KDM1A (0.83) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21335125 | 0.97 | KDM1A (0.83) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21335159 | 0.97 | KDM1A (0.79) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL14971385 | 0.97 | KDM1A (0.79) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21335122 | 0.96 | KDM1A (0.79) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL17992382 | 0.96 | KDM1A (0.79) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21335304 | 0.95 | KDM1A (0.77) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL21335161 | 0.95 | KDM1A (0.77) | KDM1ARCOR1SSTR5SSTR4SSTR2 | |
| SCHEMBL17992378 | 0.95 | KDM1A (0.77) | KDM1ARCOR1SSTR5SSTR4SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2020-06-18 | — | — | US | disclosed |
| US-10407467-B2 | Polymyxin derivatives and their use in combination therapy together with different antibiotics | NEW PHARMA LICENCE HOLDINGS LIMITED (MT) | 2019-09-10 | — | — | US | disclosed |
| US-20160222061-A1 | Polymyxin Derivatives and Their Use in Combination Therapy Together with Different Antibiotics | NEW PHARMA LICENCE HOLDINGS LIMITED (MT) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222061-A1 | Polymyxin Derivatives and Their Use in Combination Therapy Together with Different Antibiotics | MRPS18A, MRPL21, RRP1B | KDM1A 3699/4885RCOR1 1566/4885SSTR5 988/4885 |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | DDOST, MGAM, MSN | KDM1A 3829/4885RCOR1 4860/4885SSTR5 2094/4885 |
| US-10407467-B2 | Polymyxin derivatives and their use in combination therapy together with different antibiotics | MRPS18A, MRPL21, RRP1B | KDM1A 3699/4885RCOR1 1566/4885SSTR5 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.