Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895610 | 0.92 | MDM4 (0.62) | MDM4TP53KMT2ACASP3MDM2 | |
| SCHEMBL30945050 | 0.90 | MDM4 (0.60) | MDM4TP53KMT2ACASP3MDM2 | |
| SCHEMBL8897778 | 0.90 | MDM4 (0.60) | MDM4TP53KMT2ACASP3MDM2 | |
| SCHEMBL29091196 | 0.90 | MDM4 (0.60) | MDM4TP53KMT2ACASP3MDM2 | |
| SCHEMBL27651285 | 0.88 | MDM4 (0.54) | MDM4TP53KMT2ACASP3MDM2 | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL29211829 | 0.88 | MDM4 (0.54) | MDM4TP53KMT2ACASP3MDM2 | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL800078 | 0.88 | MDM4 (0.58) | MDM4TP53KMT2ACASP3MDM2 | |
| SCHEMBL21978446 | 0.88 | MDM4 (0.58) | MDM4TP53KMT2ACASP3MDM2 | |
| SCHEMBL21978443 | 0.88 | MDM4 (0.58) | MDM4TP53KMT2ACASP3MDM2 | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL120560 | 0.88 | MDM4 (0.58) | MDM4TP53KMT2ACASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |