Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091196 | 1.00 | MDM4 (0.60) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL30945050 | 1.00 | MDM4 (0.60) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL8895610 | 0.95 | MDM4 (0.62) | MDM4TP53CASP3MDM2KMT2A | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL800078 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL21978446 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL18614310 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL17992916 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL21978443 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL1002861 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL120560 | 0.90 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784950-B | Preparation method of ritalst intermediate | 广东先强药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-116874584-A | Insulin analogues | 犹他大学研究基金会 | 2023-10-13 | — | — | CN | disclosed |
| CN-110072884-B | Insulin analogues | 犹他大学研究基金会 | 2023-07-28 | — | — | CN | disclosed |
| CN-115784950-A | Preparation method of sitagliptin intermediate | 广东先强药业有限公司 | 2023-03-14 | — | — | CN | disclosed |
| EP-0770623-A1 | NOVEL CALCITONIN DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |