Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180587 | 0.95 | ENPP1 (0.59) | ENPP1CA2SMN1; SMN2CNR2PPARG | |
| SCHEMBL11106388 | 0.87 | CA2 (0.55) | ENPP1CA2SMN1; SMN2ALPLCA12 | |
| SCHEMBL3621448 | 0.86 | CA2 (0.54) | ENPP1CA2SMN1; SMN2CNR2CA12 | |
| SCHEMBL13649253 | 0.85 | ENPP1 (0.52) | ENPP1CA2SMN1; SMN2PPARGMEN1 | |
| SCHEMBL9457773 | 0.84 | ENPP1 (0.51) | ENPP1CA2SMN1; SMN2PPARGMEN1 | |
| SCHEMBL15468472 | 0.84 | ENPP1 (0.55) | ENPP1CA2SMN1; SMN2PPARGMEN1 | |
| SCHEMBL8499355 | 0.84 | ENPP1 (0.55) | ENPP1CA2SMN1; SMN2PPARGMEN1 | |
| SCHEMBL15936332 | 0.83 | ENPP1 (0.55) | ENPP1SMN1; SMN2CNR2PPARGHTT | |
| SCHEMBL6937915 | 0.83 | ENPP1 (0.58) | ENPP1CA2PPARGMEN1KMT2A | |
| SCHEMBL4326703 | 0.83 | MEN1 (0.59) | ENPP1CA2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583958-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-08-10 | — | — | EP | disclosed |