Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9886158 | 0.88 | MAPT (0.47) | MAPTNR2E1GPR35LMNAALDH1A1 | |
| SCHEMBL9885346 | 0.84 | MAPT (0.47) | MAPTNR2E1GPR35LMNAALDH1A1 | |
| SCHEMBL5773763 | 0.84 | MAPT (0.67) | MAPTNR2E1GPR35LMNAALDH1A1 | |
| SCHEMBL10751967 | 0.83 | LMNA (0.47) | MAPTNR2E1GPR35LMNAALDH1A1 | |
| SCHEMBL14075740 | 0.82 | LMNA (0.54) | MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL22573111 | 0.80 | MAPT (0.50) | MAPTGPR35LMNAALDH1A1ACP1 | |
| SCHEMBL28670019 | 0.78 | MAPT (0.47) | MAPTNR2E1GPR35LMNAALDH1A1 | |
| SCHEMBL23328069 | 0.78 | MAPT (0.59) | MAPTNR2E1GPR35LMNAALDH1A1 | |
| SCHEMBL12144643 | 0.78 | MAPT (0.54) | MAPTNR2E1GPR35LMNAACP1 | |
| SCHEMBL30977688 | 0.78 | MAPT (0.54) | MAPTNR2E1GPR35LMNAACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737811-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2016-08-10 | — | — | EP | disclosed |